The domain within your query sequence starts at position 340 and ends at position 458; the E-value for the 3i00 domain shown below is 1e-21.
TFGPPNGSMKDDRDLQIENLKREVETLRAELEKIKMEAQRYISQLKGQVNGLEAELEEQR KQKQKALVDNEQLRHELAQLKALQLEGARNQGLREEAERKASATEARYSKLKEKHSELI